Bilateral Anophthalmia in Feline

A Case of Congenital Bilateral Anophthalmia

The fate of the oculomotor system in clinical bilateral anophthalmia.

The interdependence of the development of the eye and oculomotor system during embryogenesis is currently unclear. The occurrence of clinical anophthalmia, where the globe fails to develop, permits us to study the effects this has on the development of the complex neuromuscular system controlling eye movements. In this study, we use very high-resolution T2-weighted imaging in five anophthalmic ...

Neurochemical changes in the pericalcarine cortex in congenital blindness attributable to bilateral anophthalmia.

Congenital blindness leads to large-scale functional and structural reorganization in the occipital cortex, but relatively little is known about the neurochemical changes underlying this cross-modal plasticity. To investigate the effect of complete and early visual deafferentation on the concentration of metabolites in the pericalcarine cortex, (1)H magnetic resonance spectroscopy was performed...

Neurochemical changes in the pericalcarine cortex in congenital blindness 1 due to bilateral anophthalmia

Neurochemical changes in the pericalcarine cortex in congenital blindness 1 due to bilateral anophthalmia 2 Abbreviated title: Neurochemical changes in bilateral anophthalmia 3 4 Gaelle S L Coullon, Uzay Emir, Ione Fine, Kate E Watkins, Holly Bridge. 5 6 1 FMRIB Centre, Nuffield Department of Clinical Neurosciences, University of Oxford, 7 John Radcliffe Hospital, Oxford 8 2 Department of Psych...

Compound Heterozygous VSX2 Mutation Causing Bilateral Anophthalmia in a Consanguineous Egyptian Family

Purpose: To report the clinical and genetic study of a child with bilateral anophthalmia. Methods: A 14-year-old Egyptian boy, born from consanguineous parents, underwent a general and a full ophthalmological examination. Mutation screen of the A/M genes with recessive inheritance was done stepwise and DNA was analyzed by Sanger sequencing. Results: Bilateral anophthalmia, arachnodactyly of the...